Osteoarthritis (OA) of the knee is one of the leading causes of disability at present which develops slowly and the pain it causes worsens over time.

It develops when the cartilage -- the smooth covering that protects the bones in the joint breaks down. The surface of the bones becomes damaged, causing pain, swelling, stiffness, and disability.

In people with osteoarthritis, a critical substance in synovial fluid known as hyaluronic acid breaks down. They have a lower-than-normal concentration of hyaluronic acid in their joints. Loss of hyaluronic acid appears to contribute to joint pain and stiffness. Although there is no cure for osteoarthritis, there are many treatment options available to help people manage pain and stay active.